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Northampton General Hospital NHS Trust

Medical treatment for Endometriosis

This encompasses various forms of hormone therapies designed to alleviate symptoms, particularly pain. These medications frequently exhibit the following effects:

  1. Alleviation of pain symptoms.
  2. Reduction or deceleration of the condition's progression.
  3. Postponement of disease recurrence.

It's important to note that hormonal treatments may also be associated with side effects.

Commonly used drugs include:

  • Medroxyprogesterone (Provera)
  • Progestogens
  • Norethisterone
  • GnRH analogues
  • Goserelin (Zoladex)
  • Combined oral contraceptive pill
  • Mirena intra-uterine system (IUS)
  • Depo-provera injection


While undergoing hormonal treatments, it is crucial to prevent pregnancy. Effective contraception is provided by the Mirena system, Depo-Provera, and oral contraceptive pills. However, it's important to note that other hormone treatments do not offer reliable contraception coverage. Therefore, it is recommended to use alternative contraception methods, such as the barrier method, while receiving these treatments.

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